E-cigarettes have gained popularity as a safer alternative to cigarettes; but research has shown the harmful effects of e-cigarettes on a range of cellular processes. In this study, the researchers investigated the effects of e-cigarette liquid with or without nicotine on V79 lung fibroblast cells.

The liver is the main venue for β-oxidation of fatty acids, and it maintains the balance of fat metabolism. Many studies showed that betaine regulates fat metabolism. In this work, the researchers investigated the protein metabolic profile in the liver of mice on an HF diet supplemented with 1% betaine by label free quantification analysis via LC–MS/MS.