Covalent antibody recruiting molecules are synthetic bifunctional molecules capable of inducing antibodies to recognise and eliminate cancer cells by the innate immune machinery. Learn more about this proof-of-concept research by McCann et al, and how a “covalent immune proximity-induction” strategy may enable the efficient recruitment of immune receptors via the incorporation of available modest affinity peptide ligands.
10-Hydroxydec-2-Enoic Acid Reduces Hydroxyl Free Radical-Induced Damage to Vascular Smooth Muscle Cells by Rescuing Protein and Energy Metabolism
Fan, Pei, et al. “10-Hydroxydec-2-enoic acid reduces hydroxyl free radical–induced damage to vascular smooth muscle cells by rescuing protein and...
Stoichiometry of the Gene Products From the Tetrachloroethene Reductive Dehalogenase Operon pceABCT
Cimmino, Lorenzo, et al. “Stoichiometry of the Gene Products From the Tetrachloroethene Reductive Dehalogenase Operon pceABCT.” Frontiers in microbiology 13.ARTICLE (2022): 838026....
NBS-LRR-WRKY genes and protease inhibitors (PIs) seem essential for cowpea resistance to root-knot nematode
Ribeiro, Daiane Gonzaga, et al. “NBS-LRR-WRKY genes and protease inhibitors (PIs) seem essential for cowpea resistance to root-knot nematode.” Journal of...
Hibiscus syriacus L. cultivated in callus culture exerts cytotoxicity in colorectal cancer via Notch signaling-mediated cholesterol biosynthesis suppression
Xu, Xing Yue, et al. “Hibiscus syriacus L. cultivated in callus culture exerts cytotoxicity in colorectal cancer via Notch signaling-mediated...
Widespread alterations upon exposure to the estrogenic endocrine disruptor ethinyl estradiol in the liver proteome of the marine male fish Cyprinodon variegatus
Schönemann, Alexandre M., Ricardo Beiras, and Angel P. Diz. “Widespread alterations upon exposure to the estrogenic endocrine disruptor ethinyl estradiol...
Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules
Jin, Hui, et al. “Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules.” Science advances 8.9 (2022): eabj9867. https://doi.org/10.1126/sciadv.abj9867
Variation in both proteome and N-glycoproteome of goat MFGM over lactation
Zhang, Lina, et al. “Variation in both proteome and N-glycoproteome of goat MFGM over lactation.” Journal of Food Composition and Analysis (2022):...
Multiwell photocatalytic microreactor device integrating drug biotransformation modeling and sample preparation on a MALDI target
Gorbunov, Alexander, et al. “Multiwell photocatalytic microreactor device integrating drug biotransformation modeling and sample preparation on a MALDI target.” Microchemical Journal 178...
Intracellular production of recombinant GnRH1 in yeast, Pichia pastoris, and its potential as oral treatment to advance gonadal development in juvenile orange-spotted grouper, Epinephelus coioides
Nocillado, Josephine, et al. “Intracellular production of recombinant GnRH1 in yeast, Pichia pastoris, and its potential as oral treatment to...