Extending the Mass Spectrometry-Detectable Landscape of MHC Peptides by Use of Restricted Access Material

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On 2023-02-012023-02-02By In Featured User Publications

For MS-based immunopeptidomics, major histocompatibility complex (MHC) peptides are typically isolated by immunoaffinity purification using specific anti-MHC antibodies. In this work, restricted access material (RAM)-SPE (solid-phase extraction) to increase the number of identified MHC peptides compared to C18-SPE.