Bioinformatics Solutions at US HUPO Winter 2025: Advancing Proteomics Through Innovation

Bioinformatics Solutions Inc. (BSI) was proud to attend the US HUPO Winter Conference 2025 in Philadelphia, PA, where we connected with the proteomics community to discuss the latest advancements in mass spectrometry data analysis. As a leader in bioinformatics, we showcased our cutting-edge PEAKS software suite, highlighting its latest updates designed to accelerate discovery proteomics, glycoproteomics, and targeted proteomics research.

At our booth, attendees engaged with our team in live demonstrations of PEAKS Studio 12.5, PEAKS Online, PEAKS AB 3.5, and PEAKS GlycanFinder 2.5, seeing firsthand how deep learning and AI-driven algorithms enhance peptide sequencing, protein identification, and glycan profiling.

Conference Highlights

PEAKS Studio 12.5: Pushing Discovery Proteomics Further

• Faster DIA processing with CPU/GPU optimization
• DeepNovo Peptidome workflow, bridging proteomics and genomics
• GraphNovo algorithms for improved de novo sequencing and FDR estimation
• Hybrid-PRM/DIA workflows for enhanced clinical proteomics
• Advanced quality control (QC) tools for systematic data validation

PEAKS AB 3.5: Precision in Antibody Sequencing

• Automated sequence validation with intact mass analysis
• Advanced glycan profiling for N- and O-linked glycans
• Isoleucine/Leucine differentiation via w-ion signatures
• Deep-learning-based retention time prediction for improved sequencing accuracy

PEAKS GlycanFinder 2.5: Advancing Glycoproteomics

• Comprehensive site-specific glycan profiling
• Glycan de novo sequencing for novel glycan structure identification
• PRM quantification workflows for targeted glycoproteomics
• Integrated visualization tools for glycoprotein analysis

Our participation at US HUPO Winter 2025 reinforced our commitment to empowering researchers with state-of-the-art bioinformatics solutions. Thank you to everyone who stopped by our booth—we look forward to continuing the conversation and advancing the field of proteomics together!