Mycobacterial infections remain a major global health concern, requiring fast and accurate identification for effective treatment. Due to the species diversity and...
HLA I immunopeptidome of synthetic long peptide pulsed human dendritic cells for therapeutic vaccine design
Synthetic long peptides (SLPs) are a promising candidate for therapeutic vaccine due to its characteristics. To design an effective SLP-based...
Impact of Bioinformatics Search Parameters for Peptides’ Identification and Their Post-Translational Modifications: A Case Study of Proteolysed Gelatines from Beef, Pork, and Fish
Learn how PEAKS is being used in agrifood studies for peptide and PTM identification.
Comprehensive characterization and detection of nut allergens in bakery foods using Q-TOF mass spectrometry and bioinformatics
Learn how mass spectrometry shows promise, allowing precise allergen detection.
TOF IMS mass spectrometry-based immunopeptidomics refines tumor antigen identification
Learn how immunotherapy relies on tumour antigens to stimulate anti-tumour T cell responses, and emphasises the need to identify exclusive tumour surface antigens.
Proteomic and toxicological characterization of the venoms of the most enigmatic group of rattlesnakes: The long-tailed rattlesnakes
Learn how this study further our understanding of rattlesnake venom evolutionary and how this can aid in development of effective antivenoms.
Some structural features of the peptide profile of myelin basic protein-hydrolyzing antibodies in schizophrenic patients
Learn how this study sheds light on the mechanism behind IgG's catalytic nature in acute schizophrenia cases.
Simulated in vitro digestion of α-lactalbumin modified by phosphorylation: Detection of digestive products and allergenicity
Learn how PEAKS was used to identify phosphorylation sites Bovine α-lactalbumin (BLA) and how this can effect allergic reaction of BLA.
Mistranslation of the genetic code by a new family of bacterial transfer RNAs
Learn how the researchers reported two novel families of non-canonical tRNAs, encoded by bacteria from the Streptomyces and Kitasatospora genera, that can induce mistranslation of the genetic code. These results expand the catalogue of organisms known to possess dedicated mistranslation and support the concept that mistranslation is a mechanism for increased cellular resiliency against environmental stress.
Modification of the structural stability of human serum albumin in rheumatoid arthritis
The prognosis of rheumatoid arthritis (RA) patients heavily depends on the early diagnosis and aggressive treatment, but current diagnosis cannot occur until the disease has progressed significantly. Learn how human serum albumin structure could potentially be used as a diagnostic biomarker for RA and how the molecular mechanism behind these modifications could lead to the development of new therapeutic strategies.