Welcome to the first ever PEAKS Summit Session! We are celebrating the launch of our new webinar series with a talk hosted by Qing Zhang (MSc, Software Systems Manager) entitled From Discovery to Validation: PEAKS DIA Solutions for Proteome and Peptidome.
For over 20 years, BSI has been one of the major driving forces for mass spectrometric data analysis. Through our innovative AI-based ground-breaking algorithms, we offer high accuracy solutions for general proteomics, immunopeptidomics, glycoproteomics, as well as antibody sequencing. In addition to empowering our users with cutting-edge software solutions, we offer professional CRO Lab services with particular focus on Antibody characterisations, glycoproteomics, and immunopeptidomics.
We’re thrilled to invite you to our upcoming webinar series where we delve deeper into the latest innovations within our PEAKS platforms to highlight the complete solution mass spectrometry can deliver. The PEAKS team will guide you through a range of topics, providing insights into how PEAKS and our latest developed workflows can enhance your research. We are proud of our expert team comprising scientists, AI researchers, and development teams to bring comprehensive solutions to a wide variety of research applications.
While discussing DIA, we will cover multiple opportunities and complications that occur with DIA methods. For example, since DIA MS/MS spectra are produced from a range of precursor ions within an m/z window, they are often multiplexed (contain signal from multiple peptides). This creates a unique challenge for an algorithm to identify peptides from DIA spectra. PEAKS 12 offers a deep-learning based powerful and flexible solution to this problem by allowing for peptide identification and quantification using spectral library search with or without a protein inference database, direct database search, or a combination of both for increased proteome coverage and improved FDR control. In addition, de novo sequencing can be applied to ensure no good spectra remain unidentified.
PEAKS Studio additionally offers a unique solution to DIA immunopeptidomics by incorporating high accuracy deep learning based DeepNovo peptide sequencing with database searches. Finally, a hybrid DIA-PRM provides a remarkable merged discovery and targeted proteomics in one solution.
Join us as we showcase the latest advancements in DIA and Hybrid DIA-PRM Workflows using our ever-evolving PEAKS Studio 12.