Alderley Edge, UK | February 26-27, 2025

Bioinformatics Solutions Inc. (BSI) was thrilled to participate in the SCIEX Proteomics Workshop in Alderley Edge, UK, where researchers, scientists, and industry leaders gathered to explore the latest in mass spectrometry and proteomics workflows. This hands-on workshop provided attendees with a unique opportunity to engage in live instrument demonstrations, software training, and discussions on emerging trends in proteomics.

PEAKS Software Training: Empowering Researchers

The workshop began with an optional PEAKS software training session, led by Kristina Jurcic from BSI. Attendees gained hands-on experience with PEAKS DDA and DIA solutions, including our specialized Immunopeptidome workflow, which bridges proteomics and genomics. These sessions highlighted how PEAKS leverages deep learning and AI-driven algorithms to enhance protein identification, quantification, and biomarker discovery.

ZenoTOF 7600+ and Cutting-Edge DIA Innovations

The main sessions featured insightful talks from SCIEX experts and proteomics researchers, showcasing the power of ZT Scan DIA on the ZenoTOF 7600+. The discussion covered advancements in ultrafast LC-MS, clinical proteomics applications, and hybrid DIA/PRM workflows—providing attendees with a comprehensive understanding of how next-generation mass spectrometry tools are transforming research.

Highlights from PEAKS and ZenoTOF User Talks

Leading researchers shared real-world applications of ZenoTOF and PEAKS in diverse areas of proteomics, including:

• ZT Scan DIA for bloodstream infection diagnostics (Julie Flecheux, University of Lyon)
• Precision proteomic subtyping in autoimmune diseases (Allan Stensballe, Aalborg University)
• Bioprocess optimization for CHO cell lines (Charles Eldrid, University of Manchester)
• DIA Phosphoproteomics and proteoform characterization (Brett Johnson, Imperial College London)
• Hybrid EAD-CID for N-glycoproteomics and disease research (Sib Heidelberger, SCIEX)

Hands-On Instrumentation & Data Processing

Participants had the opportunity to interact directly with SCIEX application scientists and the BSI team, engaging in:
🔬 1-hour hands-on sessions with the ZenoTOF 7600+
🖥 Live PEAKS processing sessions demonstrating ZT Scan DIA and EAD fragmentation workflows

Key Takeaways and Future Directions

The workshop concluded with roundtable discussions on standardization in DIA data analysis, AI-driven proteomics, and the future of mass spectrometry in clinical applications. The integration of hybrid fragmentation techniques, deep learning models, and high-throughput workflows is set to push the boundaries of proteomics research even further.

🚀 Thank you to SCIEX and all the researchers who joined us for this event! We look forward to continuing collaborations and driving innovation in proteomics together.